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DIabetes REmissions Clinical Trial – understanding why significant weight loss results in remission of Type 2 diabetes is at the heart of DiRECT.. Effectiveness and cost-effectiveness of mindfulness-based cognitive therapy compared with maintenance antidepressant treatment in the prevention of depressive relapse or recurrence (PREVENT): a randomised controlled trial. (PMCID:PMC4736496), Cleland, J. G.F., Freemantle, N., Eastaugh, J., Young, P. J., Harrison, J., Heran, B. S. and Taylor, R. S. 250-261. (doi: 10.1111/j.1749-4486.2009.01916.x) A systematic review and meta-analysis comparing cardiopulmonary exercise test values obtained from the arm cycle and the leg cycle respectively in healthy adults. BMC Ophthalmology, 14, (doi: 10.1186/s12962-018-0098-7) British Journal of General Practice, 66(646), 7900. 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Patients' preference for exercise setting and its influence on the health benefits gained from exercise-based cardiac rehabilitation. (2017) pp. Nurse-led interventions used to improve control of high blood pressure in people with diabetes: a systematic review and meta-analysis. Effective behavior change techniques in asthma self-care interventions: systematic review and meta-regression. (PMID:33470748) (doi: 10.1136/bmjopen-2016-012853) European Spine Journal, 28, (doi: 10.1111/j.1755-3768.2011.02312.x) The study, a two-arm, randomized controlled, parallel group, superiority trial, aimed to evaluate the implementation and effectiveness of a 12-month one-to-one volunteer mentoring program designed to improve behavioral and emotional outcomes in children aged 5 to 11 years who have teacher- and parent/carer-reported behavioral difficulties. (doi: 10.1136/bmjopen-2018-022175) Acute coronary syndromes: key role of rehabilitation and primary care in long term secondary prevention. Exercise-based cardiac rehabilitation for adults after heart valve surgery. Community-based Rehabilitation Training after stroke: protocol of a pilot randomised controlled trial (ReTrain). BMJ Open, 7(6), (PMID:29686541) International Journal of Cardiology, 162(1), Association of a difference in systolic blood pressure between arms with vascular disease and mortality: a systematic review and meta-analysis. (PMID:25098487), Anderson, L. and Taylor, R. S. pp. pp. (doi: 10.1016/S0140-6736(14)62222-4) (2015) Heart, Exercise-based cardiac rehabilitation for adults with stable angina. (PMID:22623328), Campbell, J. L., Britten, N., Green, C., Holt, T. A., Lattimer, V., Richards, S. H., Richards, D. A., Salisbury, C., Taylor, R. S. and Fletcher, E. (doi: 10.1111/j.1533-2500.2008.00234.x) 737-744. 487-495. (PMID:26176932), Gonçalves Bradley, D. C. et al. pp. 1256-1260. 7. JACC: Heart Failure, 6(7), Pain Practice, 7(3), In bipolar spectrum disorder, some individuals experience ongoing, frequent fluctuations in mood outside of affective episodes. (doi: 10.1002/14651858.CD013400), Dalal, H. M., Taylor, R. S. and Doherty, P. Clinical research in interventional pain management techniques: an epidemiologist/trialist's view. The methods are elaborated on in the published protocol. Home-based versus centre-based cardiac rehabilitation. "Flogging dead horses" : evaluating when have clinical trials achieved sufficiency and stability? (PMID:33719711) Failed back surgery syndrome: who has failed? 87-96. Gabriele Meyer1*, Sascha Kopke2, Jane Noyes3, Jackie Chandler4... PROSPERO registration of protocol latest version at: http://www.crd.york.ac.uk/PROSPERO/display_record.asp?ID=CRD42015031227. (2015) 1401-1411. Therefore we have undertaken further analysis to quantify the change in blood pressure in control arms of BP intervention studies included in th... Nurse or pharmacist-led care may improve control of hypertension. 605-622. 63. (doi: 10.1136/bmjopen-2018-025167) DiRECT is a collaboration between Professor Roy Taylor, Newcastle University and Professor Mike Lean, University of Glasgow.. One third of all people taking part were free of diabetes at 2 years. Pain Practice, 8(6), (2019) The cost-effectiveness of the Argus II retinal prosthesis in Retinitis Pigmentosa patients. (2015) Study protocol for a randomized controlled trial comparing mindfulness-based cognitive therapy with maintenance anti-depressant treatment in the prevention of depressive relapse/recurrence: The PREVENT trial, Congestive heart failure. Deep brain stimulation for Parkinson’s disease with early motor complications: a UK cost-effectiveness analysis. 12-19. (PMID:20149120), Dent, L., Taylor, R. , Jolly, K. and Raftery, J. (2017) International Journal of Sports Physical Therapy, 11(7), Factors influencing clinical trial site selection in Europe: the Survey of Attitudes towards Trial sites in Europe (the SAT-EU Study). Elite Secretarial Services was formed in January 2000. (doi: 10.1227/01.NEU.0000325731.46702.D9) (doi: 10.1016/j.pain.2008.10.008) 1-254. An exercise intervention to prevent falls in Parkinson’s : an economic evaluation. (doi: 10.1002/14651858.cd008895.pub3) BMC Musculoskeletal Disorders, 20(1), Exercise-based cardiac rehabilitation for coronary heart disease. pp. Acupuncture for ‘frequent attenders’ with medically unexplained symptoms : a randomised controlled trial (CACTUS study). Use of surrogate end points in healthcare policy: a proposal for adoption of a validation framework. Neurochirurgie, 61, (PMID:25519688) 13-29. (doi: 10.1186/1471-2261-9-13), Dretzke, J., Davenport, C., Frew, E., Barlow, J., Stewart-Brown, S., Bayliss, S., Taylor, R. S. , Sandercock, J. and Hyde, C. Angiotensin receptor blockers for heart failure. Lancet, 388(10047), Value in Health, 16(6), (PMID:29632081) : the need for case studies of the use of surrogate outcomes in cost-effectiveness analyses. Corneal neovascularization as a risk factor for graft failure and rejection after keratoplasty. (PMID:21142838), Pavey, T. G. et al. pp. (PMID:28893756) 127. pp. KEYNOTE PRESENTATIONS K1 Researching complex interventions: the need for robust approaches Peter Craig K2 Complex intervention studies: an important step in developing knowledge for practice Ingalill Rahm-Hallberg K3 Public and patient involvement in research: what, why and how? Nicotine and Tobacco Research, 18(3), (PMID:21735439) (PMCID:PMC6747864), Pio, C. S. d. A., Chaves, G., Davies, P., Taylor, R. and Grace, S. (doi: 10.1002/14651858.CD007130.pub3) (PMID:32238173) (2017) 189. BMJ Open, 8(9), Evaluation of a complex intervention (Engager) for prisoners with common mental health problems, near to and after release: study protocol for a randomised controlled trial. Health Economics, 22(2), Home-based compared with hospital-based cardiac rehabilitation in a multi-ethnic population: cost-effectiveness and patient adherence. Psychological interventions for depression and anxiety in patients with coronary heart disease, heart failure or atrial fibrillation. Routine provision of information on patient-reported outcome measures to healthcare providers and patients in clinical practice. pp. Topical diclofenac and its role in pain and inflammation: an evidence-based review. (doi: 10.1186/1756-0500-6-324) (2021) Personalised rehabilitation for cardiac and pulmonary patients with multimorbidity: time for implementation? It's not the years in your life that matters, it's the life in your years. on behalf of the BRUM Trial Steering Committee, . 1946-1947. pp. Effect of exercise referral schemes in primary care on physical activity and improving health outcomes : systematic review and meta-analysis. Effects of cardiac rehabilitation in low- and middle-income countries: a systematic review and meta-analysis of randomized controlled trials. (2016) (doi: 10.1186/1745-6215-15-217) (doi: 10.1002/14651858.CD002902.pub4) Meta-analyses of randomized controlled trials show suboptimal validity of surrogate outcomes for overall survival in advanced colorectal cancer. Prevalence of systolic inter-arm differences in blood pressure for different primary care populations: systematic review and meta-analysis. An increasingly important approach is the meta-analysis of individual participant data (IPD) where the raw individual-level data are obtained for each study and used... Background: Evaluating Augmented Depression Therapy (ADepT): study protocol for a pilot randomised controlled trial. Post-myocardial infarction education is effective but not enough on its own. (2010) 13. Open Heart, 3(2), (2011) (doi: 10.1002/14651858.cd003331.pub5) To identify and explore change processes explaining the effects of the Rehabilitation Enablement in Chronic Heart Failure (REACH-HF) intervention taking account of reach, amount of intervention received, delivery fidelity and patient and caregiver perspectives. A cross-sectional survey from England, Wales and Northern Ireland, COCOA: Care for Offenders Continuity of Access. (doi: 10.1038/s41598-018-26279-7) Reduced dietary salt for the prevention of cardiovascular disease. (PMCID:PMC5738974), Wyatt, K. et al. , Liu, Z. and Stein, K. 229-239. (PMCID:PMC5848446), Long, L., Anderson, L., Dewhirst, A. M., He, J., Bridges, C., Gandhi, M. and Taylor, R. S. pp. CD008895. Patients' perception of postoperative pain management: validation of the international pain outcomes (IPO) questionnaire. Multicentre, double-blind, randomised, sham-controlled trial of 10 khz high-frequency spinal cord stimulation for chronic neuropathic low back pain (MODULATE-LBP): a trial protocol. (PMCID:PMC5541595), Anderson, L., Sharp, G. A., Norton, R. J., Dalal, H., Dean, S. G., Jolly, K., Cowie, A., Zawada, A. and Taylor, R. S. pp. Pain, 155(7), (PMID:20126968) 6-13. (PMID:22103683), Ciani, O. and Taylor, R.S. Psychological interventions for coronary heart disease: cochrane systematic review and meta-analysis. (2019) Health Technology Assessment, 19(13), Cochrane Database of Systematic Reviews, 2019(2), (2011) Dose-response relation between dietary sodium and blood pressure: a meta-regression analysis of 133 randomized controlled trials. e016844. (2008) CD007131. Health technology assessment of medical devices: a survey of non-European Union agencies. Home-based rehabilitation for heart failure with reduced ejection fraction: mixed methods process evaluation of the REACH-HF multicentre randomised controlled trial. Characterizing the somatosensory profile of patients with failed back surgery syndrome with unilateral lumbar radiculopathy undergoing spinal cord stimulation: a single center prospective pilot study. International Journal of Therapy and Rehabilitation, 26(2), Can municipality-based post-discharge follow-up visits including a general practitioner reduce early readmission among the fragile elderly (65+ years old)? ... 6 Il razionale che porta il ricercatore a scegliere i MM può essere diverso, ad esempio quando i risultati di uno studio possono essere ampliati e approfonditi attraverso una seconda fonte di dati oppure quando né un disegno di ricerca qualitativo né quantitativo sono in grado di rispondere appieno alla complessità del problema di ricerca: la ricerca infermieristica studia infatti fenomeni com-plessi. Journal of Clinical and Experimental Cardiology. (PMID:29212370), Richards, S. H. et al. S66-S76. Cochrane Database of Systematic Reviews, 2014(7), (2014) (doi: 10.1016/j.hfc.2014.08.012) BMC Cardiovascular Disorders, 9, Equally, while reviews generally found a positive impact from pharmacist intervention, meta-analysis often did not examine the specific overall effect of community pharmacists, as distinct from pharmacists intervening in other settings. COVID-19 and its cardiovascular effects: a systematic review of prevalence studies. (PMCID:PMC6767391), Desai, M., Bentley, A., Keck, W. A., Haag, T., Taylor, R. S. and Dakin, H. (PMID:30720582) Cancer Epidemiology, 64, Cochrane corner: increasing patient utilisation of cardiac rehabilitation. (PMID:29394453) Exercise training for systolic heart failure: Cochrane systematic review and meta-analysis. Exercise-based cardiac rehabilitation for adults with atrial fibrillation. Cochrane Database of Systematic Reviews, 2010(1), 92-96. Generating evidence on spinal cord stimulation for failed back surgery syndrome: Not yet fully charged. (PMID:23279591), Jenkinson, C. E., Dickens, A. P., Jones, K., Thompson-Coon, J., Taylor, R. S. , Rogers, M., Bambra, C. L., Lang, I. and Richards, S. H. (doi: 10.1185/03007995.2010.541022) (2017) (PMID:25432474), Ciani, O., Wilcher, B., Blankart, C. R., Hatz, M., Rupel, V. P., Erker, R. S., Varabyova, Y. and Taylor, R. S. Denmark, and implications for policy makers for ‘ frequent attenders ’ with medically unexplained symptoms: pilot... Interventions: systematic review and meta-analysis for complex interventions and medical devices and drugs: are they different. Care: a systematic review and meta-analysis comparing Cardiopulmonary exercise test values obtained from arm! Of cardiovascular disease outcomes and mortality implications 3, CD010876: PMC5072922 ) Thompson! And Bujkiewicz, S. H. et al COPD and chronic neuropathic pain are sustained: qualitative! 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