Please read the Topical Use Safety section of this article (above) before using. Retrieved from, https://naturalmedicines.therapeuticresearch.com/databases/food,-herbs-supplements/professional.aspx?productid=295. Choose a supplement tested by a trusted third party, such as USP, ConsumerLabs, or NSF when possible. Do not use this product without medical advice if you are breast-feeding a baby. Like any new treatment, discontinue use if any irritation occurs. Whether you are treated by a medical doctor or a practitioner trained in the use of natural medicines/supplements, make sure all your healthcare providers know about all of your medical conditions and treatments. Hybrids and other species may have a similar appearance but could have significantly different amounts of the toxic pyrrolizidine alkaloids (Kucera et al., 2018). Do not give any herbal/health supplement to a child without medical advice. View abstract. The review included one study of 220 people with knee osteoarthritis, a degenerative "wear-and-tear" joint condition. Comfrey shouldn't be used in any form during pregnancy or nursing due to the risk of liver damage to infants. Effect of a blend of comfrey root extract (Symphytum officinale L.) and tannic acid creams in the treatment of osteoarthritis of the knee: randomized, placebo-controlled, double-blind, multiclinical trials. In some cases, ointments with comfrey have caused redness, itching, and a rash (Smith, 2011). J Toxicol Environ Health B Crit Rev. Cochrane Database Syst Rev. International Journal of Pediatrics and Adolescent Medicine, (4), 135-141. https://doi.org/10.1016/j.ijpam.2018.11.002. The leaves and stems of comfrey contain pyrrolizidine alkaloids that can cause toxic damage if ingested in excess (Ulbricht, 2010). Buy 1 get 1 Half Price on Vitamins & Supplements, Popular Vitamins & Supplements Subscriptions, Buy 1 get 1 Half Price gut health supplements, Guide to sleeping better natural sleeping remedies, Living in the now, gut health & mental wellbeing, The thing that makes you different makes you special, Bhupesh Panchal, Senior Regulatory Affairs Associate, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5908267/, http://www.missouribotanicalgarden.org/PlantFinder/PlantFinderDetails.aspx, http://www.sciencedirect.com/science/article/pii/S0965229913001672, http://www.ncbi.nlm.nih.gov/pubmed/22887778, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363250/, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6631335/, https://pubmed.ncbi.nlm.nih.gov/22887778/, https://www.ema.europa.eu/en/documents/herbal-report/final-assessment-report-symphytum-officinale-l-radix_en.pdf, http://pennstatehershey.adam.com/content.aspx?productid=107&pid=33&gid=000234. The internal or extensive topical use of comfrey cannot be recommended because of numerous reports of liver damage. This could change the effects and side effects of comfrey. View abstract. It also covers side effects, interactions, and what to look for. Study results revealed that pain intensity during active movement decreased an average of 95.2% in the group given comfrey ointment. Comfrey contains chemicals called. These include allantoin, rosmarinic acid, and others. Aust.Fam.Physician 2008;37(4):235-236. When the root is boiled in water, it forms a sticky, glue-like paste. Koll, R., Buhr, M., Dieter, R., Pabst, H., Predel, H. G., Petrowicz, O., & Staiger, C. (2004). Influence of moderate physical exertion on subacute low back pain, after Symphytum officinale ointment treatment. Capsicum Cream Holland And Barrett Recipes View abstract. 2017;65(1):363-373. doi:10.1002/hep.28813. After 2-4 weeks have passed, strain the root from the alcohol using a coffee filter inserted in a wire mesh strainer or similar setup. Predel, H. G., Giannetti, B., Koll, R., Bulitta, M., and Staiger, C. Efficacy of a comfrey root extract ointment in comparison to a diclofenac gel in the treatment of ankle distortions: results of an observer-blind, randomized, multicenter study. Homeopathy. Comfrey cream combines ingredients like oils or water and glyceryl stearate with Symphytum officinale (comfrey) extracts. As an additional measure of efficacy, groups instructed to use the comfrey preparation for the longest period of time experienced the most improvement. Avoid with medications that induce CYP3A4 or are hepatotoxic (Natural Medicines, 2020). 2020;142:104519. Turley, A. J. and Muir, D. F. ECG for physicians: a potentially fatal case of mistaken identity. Comfrey oil shouldnt be used for cooking, like other types of cooking oil. It should never be taken by mouth. Phytomedicine, 14(1), 2-10. https://doi.org/10.1016/j.phymed.2006.11.006, Jedlinszki, N., Balzs, B., Csnyi, E., & Csupor, D. (2017). Find out how to use it here along with its benefits. Tolerability and effectiveness of an antitrauma cream with comfrey herb extract in pediatric use with application on intact and on broken skin. In a small study with 30 subjects, lower back pain from exercise was reduced with an ointment containing comfrey. Quis autem velum iure reprehe nderit. Penetration of lycopsamine from a comfrey ointment through human epidermis. Comfrey is likley unsafe to take by mouth. Phytother Res. Comfrey has been used medicinally for at least 2000 years for various conditions, including bone fractures, ulcers, and gout. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Comfrey's original name, knitbone, derives from the external use of poultices of its leaves and roots to heal burns, sprains, swelling, and bruises. View abstract. When buying commercial brands, seek those that have had the pyrrolizidine alkaloids removed, if possible. Inhibition of prostaglandin biosynthesis and PAF-induced exocytosis. Amendments to the poison list. J Agric.Food Chem 2001;49(8):3942-3946. Dietary Supplements: What You Need to Know. After eight days, the group that used the cream had significantly less pain than those who had the placebo. A large review released in 2013 about the medicinal uses of comfrey stated: It is clinically proven to relieve pain, inflammation and swelling of muscles and joints in the case of degenerative arthritis, acute myalgia in the back, sprains, contusions and strains after . However, even if supplements are third-party tested, that doesn't mean they are necessarily safe for all or effective in general. Barna, M., Kucera, A., Hladikova, M., & Kucera, M. (2012). Comfrey may be used topically as a cream, ointment, salve, or paste. What alternatives to comfrey cream are there for back pain? This is because only a small amount of the pyrrolizidine alkaloids are absorbed through the skin (Jedlinszki et al., 2017). Symphytum species: A comprehensive review on chemical composition, food applications and phytopharmacology. Stop using comfrey and call your healthcare provider at once if you have: liver problems--nausea, upper stomach pain, itching, tired feeling, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes). Comfrey root: from tradition to modern clinical trials, Efficacy and safety of comfrey root extract ointment in the treatment of acute upper or lower back pain: results of a double-blind, randomised, placebo-controlled, multicentre trial, Topical herbal therapies for treating osteoarthritis, Effect of a blend of comfrey root extract (Symphytum officinale L.) and tannic acid creams in the treatment of osteoarthritis of the knee: randomized, placebo-controlled, double-blind, multiclinical trials, Treatment with 4Jointz reduces knee pain over 12 weeks of treatment in patients with clinical knee osteoarthritis: a randomised controlled trial. Need some help with an order or want to speak to a member of our Customer Services team? Comfrey cream combines ingredients like oils or water and glyceryl stearate with Symphytum officinale (comfrey) extracts. Amazon.com: Comfrey Cream The chemicals contained in comfrey may cause birth defects. 2012;101(4):211-216. In a randomized, controlled, double-blind study with 203 patients, applications of a 10% comfrey cream were well tolerated, reduced swelling and pain, and improved mobility (Kucera et al., 2004). After testing their 1000mg CBD oil drops for over a month, we now have little question this is the best CBD oil within the UK as of 2019. These third-party organizations test products to ensure they were manufactured safely and contain the ingredients indicated on the labeling without contaminants. doi:10.1002/ptr.4612, Salehi B, Sharopov F, Boyunegmez Tumer T, et al. However, further well-designed studies are needed. A significant reduction in pain was observed in the groups using the comfrey product. In a randomized, double-blind, placebo-controlled trial, 220 patients with knee osteoarthritis used either a commercial topical comfrey root extract or a placebo. Read our. Available at: https://www.cfsan.fda.gov/~dms/dspltr06.html. Thank you, {{form.email}}, for signing up. Book your free, one-to-one online consultation with one of our qualified advisors. Efficacy of a comfrey root extract ointment in comparison to a Diclo-fenac gel in the treatment of ankle distortions: Results of an observer-blind, randomized, multicenter study. Thus, it is not advised to ingest herbal preparations of comfrey unless guided by an expert pharmacologist and physician. Eucalyptus oil is used externally to stimulate blood flow. Available for Android and iOS devices. Add cup of the comfrey tincture and all essential oils to the cooled oil/butter mixture. Predel, H. G., Giannetti, B., Koll, R., Bulitta, M., & Staiger, C. (2005). A later study of 133 peoplefound some evidence that a topical combination of comfrey extract and tannic acid led to reduced knee pain. Herbal drugs and phytopharmaceuticals. https://doi.org/10.1007/s10354-007-0474-y. Arzneimittelforschung, 62(06), 285-289. https://doi.org/10.1007/s10354-007-0474-y, Giannetti, B. M., Staiger, C., Bulitta, M., & Predel, H. G. (2010). Heard about essential oils but not quite sure about what they can do for you? All rights reserved. How to make a natural healing comfrey cream - Simply Comfrey Palestrica of the Third Millennium Civilization & Sport, 14(3). Make sure to always buy comfrey (Symphytum officianale) root and leaf from a trusted source. Pharmazie 1995;50:83-98. A limited number of clinical trials show short-term efficacy of topically applied, alkaloid-free comfrey preparations in skin abrasions and inflammatory conditions. Select a condition to view a list of vitamins. View abstract. Store comfrey cream according to package instructions, typically at room temperature and out of reach of children and pets. The ankle swelling decreased by 79.5% in the comfrey root group and 69.4% in the diclofenac group. Rad. Mazzocchi, A. and Montanaro, F. Observational study of the use of Symphytum 5CH in the management of pain and swelling after dental implant surgery. hollandandbarrett.ie is a trading name of Holland & Barrett Retail Limited. radix) extract ointment in the treatment of patients with painful osteoarthritis of the knee: Results of a double-blind, randomised, bicenter, placebo-controlled trial. However, comfrey can also contain toxic substances called pyrrolizidine alkaloids that cause liver damage, cancer, and death. My family has used comfy for ingrown toenails. Other drugs may interact with comfrey, including prescription and over-the-counter medicines, vitamins, and herbal products. Comfrey is a flowering shrub that grows in Europe, Asia and, now, North America. A handbook for practice on a scientific basis. Mosby Elsevier. Double boiler Comfrey is changed and broken down by the liver. Bleakley, C. M., McDonough, S. M., and MacAuley, D. C. Some conservative strategies are effective when added to controlled mobilisation with external support after acute ankle sprain: a systematic review. Barna, M., Kucera, A., Hladicova, M., and Kucera, M. [Wound healing effects of a Symphytum herb extract cream (Symphytum x uplandicum NYMAN: ): results of a randomized, controlled double-blind study]. Transfer the cooled oil and butter mixture to a standing electric mixer or blender. Comfrey Uses, Side Effects & Warnings - Drugs.com Comfrey is traditionally used for the symptomatic treatment of minor sprains and bruises and is also known for its healing properties. Cbd Oil In Holland And Barrett. Comfrey ( Symphytum officinale) is an attractive ornamental plant used in gardening and medicine. Comfrey (Symphytum officinale) is a plant with yellow or purple flowers found in Europe, Asia, and North America. This was compared to 37.8% in the placebo group. Discard after a year or according to labeling. Be sure to use comfrey root from a reputable source that has properly identified the species. A member of the borage family, comfrey root, leaves, and stems have an obvious coat of bristly hair. Book your free, one-to-one online consultation with one of our qualified advisors. Electric bowl mixer (like a KitchenAid) or a blender, Small glass jars with lids for sharing (optional). How do you use it and are there any side effects? Please simply create an account before buying/booking any courses. 2758955. It's found in Europe, Asia, and North America. 4.3 4.3 out of 5 stars (225) $19.95 $ 19. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. WebMD does not provide medical advice, diagnosis or treatment. Other alternative therapies may help to ease the pain. Complementary Health Approaches for Chronic Pain: What the Science Says. Drugs and Lactation Database (LactMed). Sowa I, Paduch R, Strzemski M, et al. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed. It contains chemicals that are poisonous. Do not use more of this product than is recommended on the label. comfrey cream holland and barrettfeathered friend questions and answers. The Effect of Comfrey on Enoxaparin-Induced Bruise in Patients with Acute Coronary Syndrome: A Randomised Clinical Trial. 1/8 cup comfrey tincture (Symphytum officinale), store bought or via recipe, above. This item: Terry Naturally Traumaplant Comfrey Cream - 1.76 oz (50 g) - Non-Staining Topical Botanical, Free of Toxic Pyrrolizidine Alkaloids (PAs) & Parabens - for External Use Only $20.76 ($11.80/Ounce) Dr. Christopher's Comfrey Ointment, 2 Ounce $11.99 ($6.00/Ounce) Dr Christopher's Formula Complete Tissue and Bone Ointment, 4 Ounce With extract of Comfrey. Efficacy and safety of comfrey root extract ointment in the treatment of acute upper or lower back pain: Results of a double-blind, randomised, placebo controlled, multicentre trial. It produces clusters of purple, blue, and white flowers, and it's famous for its long . 2011;10(3):147-56. doi:10.1016/j.jcm.2011.01.003, Laslett LL, Quinn SJ, Darian-Smith E, et al. Wien Med Wochenschr. Therapeutic use of comfrey is limited because of its toxicity. Lorem ipsum dolor sit nulla or narjusto laoreet onse ctetur adipisci. Jedlinszki, N., Balzs, B., Csnyi, E., & Csupor, D. (2017). Please read the Topical Use Safety section of this article (above) before using. Its ready when the mixture has solidified somewhat and has a cloudy, creamy, and slightly runny consistency. We comply with the HONcode standard for trustworthy health information. In another study, participants with ankle sprains received either comfrey root extract cream or diclofenac gel, a nonsteroidal anti-inflammatory drug (NSAID). Avoid comfrey with certain medical conditions, such as liver disease. Wien.Med Wochenschr. Copyright Holland & Barrett Retail Limited, 2022. Staiger, C. Comfrey root: from tradition to modern clinical trials. Efficacy of a comfrey root (Symphyti offic. The comfrey plant, Symphytum officinale, gets its name from the Latin confervere, meaning to grow together. State Level Environment Impact Assessment Authority, Jharkhand radix) extract ointment in the treatment of patients with painful osteoarthritis of the knee: results of a double-blind, randomised, bicenter, placebo-controlled trial. Giannetti, B. M., Staiger, C., Bulitta, M., & Predel, H. G. (2010). MedlinePlus Medical Encyclopedia. Comfrey [Online article]. Frost R, O'meara S, Macpherson H. The external use of comfrey: a practitioner survey. Whether youre familiar with it or not, this unusual herbal remedy is definitely worth knowing more about. As we are constantly reviewing and developing our products to meet our consumer needs, consumers, particularly those that suffer from allergies and intolerances, should always check product labelling, warnings, and directions provided with the product that is delivered, prior to use or consumption. Credit Solution Experts Incorporated offers quality business credit building services, which includes an easy step-by-step system designed for helping clients build their business credit effortlessly. Finally, well warn of any side effects associated with comfrey oil. Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. This is done by soaking the root in at least 50% alcohol for a minimum of two weeks. Grube, B., Grunwald, J., Krug, L., and Staiger, C. Efficacy of a comfrey root (Symphyti offic. Therapeutic Research Faculty 2020. Tunon, H., Olavsdotter, C., and Bohlin, L. Evaluation of anti-inflammatory activity of some Swedish medicinal plants. Additionally, there is scientific research demonstrating comfreys effectiveness at soothing muscle and joint pain, some of which are highlighted in this post. Label with the ingredients and date made. 2017;83:1-4. View abstract. Set on a sunny windowsill and shake once a day for 2-4 weeks. The recipe makes about 5 cups of whipped creamy lotion. As we are constantly reviewing and developing our products to meet our consumer needs, consumers, particularly those that suffer from allergies and intolerances, should always check product labelling, warnings, and directions provided with the product that is delivered, prior to use or consumption.